Staying awake takes active work from the brain. Even after a full night’s sleep, alertness depends on nerve cells exchanging chemical signals. One of those signals comes from orexin, a pair of naturally occurring peptides that help the brain maintain wakefulness.
A peptide is a short chain of amino acids. Orexin comes in two forms, orexin-A and orexin-B, produced by a relatively small group of nerve cells in the hypothalamus. These cells connect with areas of the brain involved in alertness. Researchers are interested in how such a small population of cells…
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